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What is the IRB?

Advocate Health Care (AHC) is committed to promoting the safety, dignity, and welfare of adults and children who participate in human subject research. This includes achieving meaningful informed consent at the outset of a particular study and throughout the course of research.

Human subject research at Advocate requires review and approval by the Institutional Review Board (IRB). The IRB also monitors research from the time of approval until a study ends. An independent ethics committee, the IRB is composed of scientist and non-scientist members drawn from within Advocate and from the surrounding community.

The primary responsibility of Advocate’s IRB is to protect human subjects. This entails reviewing and monitoring all human research at inpatient and outpatient Advocate sites. The IRB is subject to internal review within Advocate and also from federal agencies such as the Food and Drug Administration and the Office for Human Research Protections (Department of Health and Human Services).

Advocate’s IRB staff provides education and regulatory guidance to the board, investigators, and members of the research team. Individuals who volunteer to participate in research may also contact the IRB office when they have questions about their participation in a particular study or about their rights as research subjects.


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