The pediatric ophthalmology division at Advocate Hope Children's Hospital provides advanced ophthalmology services for children. Surgical and treatment capabilities address strabismus (eye crossing or other malpositioning) and amblyopia, genetic and heritable ocular diseases, pediatric cataracts, pediatric ocular tumors, pediatric ptosis (eyelid drooping), congenital nasolacrimal duct obstruction, pediatric ocular trauma, pediatric glaucoma, cranial nerve palsies and retinopathy of prematurity.

Hope Children's Hospital is one of the few hospitals in Illinois equipped to perform retinopathy of prematurity laser treatment in the nursery (rather than transporting premature babies to the operating room). The division provided regional leadership for a multi-center NIH study of early treatment of retinopathy of prematurity. In addition, the pediatric opthalmology section has conducted original research on silicone tube treatment of tear duct obstruction.

The ophthalmology team at Hope Children's Hospital is one of the few in the Chicago area experienced in pediatric cataract surgery with intraocular lens implantation. They are also part of the hospital's craniofacial treatment team and participate with other subspecialists in the evaluation and treatment of children with special problems, including Down syndrome, cerebral palsy, autism and school-related vision disorders.